Diabetes prolongs hospitalization and increases infection, cerebral edema, and neurological complications in meningioma patients: A retrospective study

Table 4 Comparison of infection between two groups of patients, n (%)/mean ± SD

Parameters	Diabetics group (n = 105)	Non-diabetics group (n = 411)	t/χ2	P value
Grading of wound healing			35.698	< 0.001
Primary wound healing without infection	73 (69.52)	376 (91.48)
Secondary and tertiary wound healing with infection	32 (30.48)	35 (8.52)
Pre-operative blood glucose (mg/dL)	151.54 ± 17.61	119.85 ± 15.93	17.795	< 0.001
Post-operative blood glucose (mg/dL)	190.50 ± 14.20	189.70 ± 12.40	0.572	0.568
Preoperative albumin (mg/L)	378.42 ± 13.41	379.52 ± 13.51	0.750	0.454
Postoperative albumin (mg/L)	291.78 ± 13.10	300.97 ± 13.72	6.185	< 0.001
Preoperative platelet count (109/L)	145.52 ± 7.41	145.42 ± 6.68	0.134	0.894
Postoperative platelet count (109/L)	269.08 ± 6.62	266.67 ± 7.44	3.019	0.003
Preoperative white blood cell count (109/L)	5.93 ± 1.24	5.83 ± 1.31	0.671	0.502
Postoperative white blood cell count (109/L)	15.61 ± 4.98	14.52 ± 3.63	2.104	0.037
Preoperative CRP (mg/L)	3.21 ± 1.31	2.96 ± 1.01	1.815	0.072
Postoperative CRP (mg/L)	133.94 ± 18.12	128.63 ± 18.24	2.664	0.008
Preoperative IL-6 (ng/mL)	20.53 ± 2.23	20.16 ± 2.63	1.475	0.142
Postoperative IL-6 (ng/mL)	28.42 ± 5.67	27.26 ± 5.41	1.945	0.052
Preoperative TNF-α (pg/mL)	51.35 ± 7.56	50.85 ± 7.78	0.591	0.555
Postoperative TNF-α (pg/mL)	61.17 ± 7.42	59.31 ± 7.52	2.267	0.024

CRP: C-Reactive Protein; IL-6: Interleukin-6; TNF-α: Tumor necrosis factor-alpha.