Integrated hepatic transcriptome and metabolome reveal the mechanisms of Jiangtang Tiaozhi formula on improving glycolipid metabolic disorder

Table 2 The specific information of these potential genes

No.	Gene ID	Gene name	Model vs control		JTTZF vs model		Pathway
			log2FC	Trend	log2FC	Trend
1	ENSMUSG00000020038	Cry1	-1.65	Db	1.92	Ub
2	ENSMUSG00000055730	Ces2a	-3.09	Db	1.64	Ub	Pathway1
3	ENSMUSG00000056973	Ces1d	-1.91	Db	1.91	Ub
4	ENSMUSG00000029816	Gpnmb	3.55	Ub	-2.79	Db
5	ENSMUSG00000024526	Cidea	4.14	Ub	-2.99	Db
6	ENSMUSG00000008734	Gprc5b	1.73	Ub	-2.15	Db
7	ENSMUSG00000062515	Fabp4	1.52	Ub	-1.58	Db	Pathway2,3
8	ENSMUSG00000028773	Fabp3	4.51	Ub	-2.90	Db	Pathway2

^bP < 0.01.

¹Drug metabolism other enzymes.

²Peroxisome proliferators-activated receptor signaling pathway.

³Regulation of lipolysis in adipocytes.

JTTZF: Jiangtang Tiaozhi formula; D: Down-regulated; U: Up-regulated; FC: Fold change.