Association of serum oncostatin M with disease severity and mortality in community-acquired pneumonia with diabetes mellitus

Table 4 Area under the curve and thresholds for predicting 1-year mortality in community-acquired pneumonia patients with diabetes mellitus

Variable	AUC	95%CI		Sensitivity (%)	Specificity (%)	Threshold	P value
		Lower limit	Upper limit
IL-6 (pg/mL)	0.596	0.458	0.733	64.7	67.1	> 9.10	0.222
IL-8 (pg/mL)	0.721	0.574	0.868	76.5	75.7	> 23.60	0.005
OSM (pg/mL)	0.738	0.622	0.854	82.4	62.9	> 35.62	0.002
PCT (μg/L)	0.751	0.606	0.897	82.4	75.7	> 0.28	0.001
CRP (mg/L)	0.575	0.420	0.730	17.6	98.6	> 233.92	0.341
WBC (× 109/L)	0.724	0.592	0.856	82.4	62.9	> 8.92	0.004
NEU (× 109/L)	0.748	0.628	0.868	82.4	62.9	> 7.12	0.002
NLR	0.718	0.583	0.845	82.4	55.7	> 5.05	0.005
CURB-65	0.879	0.803	0.955	94.1	74.3	> 1.5	< 0.0001
PSI score	0.882	0.788	0.975	88.2	81.4	> 109.50	< 0.0001
CURB-65 + OSM	0.903	0.837	0.970	94.1	82.9	> 0.21	< 0.0001
PSI score + OSM	0.879	0.784	0.974	88.2	77.1	> 0.17	< 0.0001

AUC: Area under the curve; CI: Confidence interval; IL-6: Interleukin-6; IL-8: Interleukin-8; OSM: Oncostatin M; PCT: Procalcitonin; CRP: C-reactive protein; WBC: White blood cell; NLR: Neutrophil-to-lymphocyte ratio; NEU: Neutrophil; CURB-65: Confusion, uremia, respiratory rate, blood pressure, and age ≥ 65 years; PSI: Pneumonia severity index.