Association of serum oncostatin M with disease severity and mortality in community-acquired pneumonia with diabetes mellitus

Table 2 Comparisons of clinical characteristics and outcomes among diabetes mellitus-community-acquired pneumonia patients, mean ± SD/n (%)/median (interquartile range)

Characteristics	NSCAP (n = 61)	SCAP (n = 26)	P value
Sex, male	38 (62.30)	19 (73.10)	0.333
Age ≥ 65 years	33 (54.10)	22 (84.62)	0.007
Underlying disease(s)
Chronic heart diseases	26 (42.62)	17 (65.38)	0.052
Hypertension	43 (70.49)	19 (73.08)	0.807
Chronic renal diseases	4 (6.56)	1 (3.85)	1.000
Cerebrovascular diseases	9 (14.75)	13 (50.00)	0.001
Chronic pulmonary diseases	7 (11.48)	2 (7.69)	0.899
Laboratory results
WBC (× 109/L)	7.47 (6.11-10.70)	12.46 (9.51-14.88)	< 0.001
NEU (× 109/L)	4.86 (3.69-7.87)	10.69 (7.50-12.93)	< 0.001
LYM (× 109/L)	1.41 (0.96-2.01)	0.92 (0.52-1.64)	0.058
NLR	3.48 (1.95-8.36)	10.77 (5.26-40.28)	< 0.001
CRP (mg/L)	39.18 (10.60-117.67)	51.14 (16.40-105.65)	0.330
PCT (μg/L)	0.09 (0.05-0.25)	0.38 (0.17-1.59)	0.003
ALB (g/L)	37.39 (32.14-40.23)	32.81 ± 5.23	0.007
Cr (μmol/L)	72.66 (63.27-86.53)	100.80 (66.92-153.10)	0.009
BUN (mmol/L)	5.62 (4.70-7.07)	9.70 (8.13-19.19)	< 0.001
Oncostatin M (pg/mL)	26.89 (11.03-58.93)	56.29 (35.59-139.19)	0.001
Interleukin-6 (pg/mL)	4.74 (2.77-13.84)	11.00 (4.71-17.65)	0.020
Interleukin-8 (pg/mL)	14.91 (12.24-23.02)	26.85 (20.19-49.61)	0.001
CURB-65 score	1 (0-1)	3 (2-3)	< 0.001
PSI score	71.00 (59.50-87.50)	137.50 (121.25-156.75)	< 0.001
In-hospital mortality	0 (0)	4 (15.38)	0.007
1-year mortality	2 (3.28)	15 (57.69)	< 0.001

Variables are expressed as n (%); mean ± SD for continuous variables conforming to a normal distribution; and median (interquartile range) for continuous nonparametric data. SCAP: Severe community-acquired pneumonia; NSCAP: Non-severe community-acquired pneumonia; WBC: White blood cell; NEU: Neutrophil; LYM: Lymphocyte; CRP: C-reactive protein; NLR: Neutrophil-to-lymphocyte ratio; PCT: Procalcitonin; ALB: Albumin; Cr: Creatinine; BUN: Blood urea nitrogen; CURB-65: Confusion, uremia, respiratory rate, blood pressure, and age ≥ 65 years; PSI: Pneumonia severity index.