Cluster analysis of computed tomography identifies duration-associated abdominal fat deposition in type 2 diabetes mellitus

doi:10.4239/wjd.124565

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World Journal of Diabetes

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1948-9358

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Observational Study

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World J Diabetes. Nov 15, 2026; 17(11): 124565
Published online Nov 15, 2026. doi: 10.4239/wjd.124565

Table 2 Comparison of computed tomography values of different abdominal organs and fat area, mean ± SD

CT value or fat area values	Healthy group	Prediabetes group	DMa group	DMb group	P value
Liver (HU)	59.57 ± 5.30	54.45 ± 7.63	51.31 ± 8.41	51.22 ± 7.53	0.000^a
Spleen (HU)	47.24 ± 4.64	46.15 ± 5.10	46.96 ± 4.95	46.65 ± 4.81	0.263^a
Head of pancreas (HU)	42.33 ± 7.31	37.86 ± 9.06	36.64 ± 10.18	35.09 ± 10.30	0.000^a
Body of pancreas (HU)	42.65 ± 7.44	38.79 ± 9.03	37.20 ± 9.51	35.98 ± 7.94	0.000^a
Tail of pancreas (HU)	42.57 ± 5.87	38.58 ± 8.76	34.71 ± 9.93	33.53 ± 9.74	0.000^a
Renal parenchyma (HU)	29.72 ± 4.27	30.38 (25.28, 35.48)	30.89 ± 3.64	31.18 (25.50, 36.86)	0.015^a
L3 vertebral body (HU)	140.68 (69.20, 212.16)	120.38 (55.53, 185.23)	123.43 ± 44.14	98.29 (39.83, 156.75)	0.000^a
Psoas major (HU)	49.75 ± 5.71	47.97 ± 7.66	45.60 ± 6.99	43.65 (32.44, 54.86)	0.000^a
VAT (mm²)	94.80 (66.95, 122.65)	114.78 ± 43.14	119.67 (54.13, 185.21)	111.73 (45.37, 178.09)	0.000^a
SAT (mm²)	90.51 (61.66, 119.36)	144.35 ± 73.00	127.70 (18.30, 237.10)	135.40 (52.52, 218.28)	0.000^a
Renal sinus fat area (mm²)	1.47 ± 0.56	1.64 ± 0.63	1.79 ± 1.10	2.19 ± 1.16	0.000^a

^aP < 0.05.

CT: Computed tomography; DMa: Type 2 diabetes mellitus with disease duration < 5 years; DMb: Type 2 diabetes mellitus with disease duration ≥ 5 years; VAT: Visceral adipose tissue; SAT: Subcutaneous adipose tissue.

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Citation: Yang FZ, Li HY, Li G, Zhang YL, Ji Q. Cluster analysis of computed tomography identifies duration-associated abdominal fat deposition in type 2 diabetes mellitus. World J Diabetes 2026; 17(11): 124565
URL: https://www.wjgnet.com/1948-9358/full/v17/i11/124565.htm
DOI: https://dx.doi.org/10.4239/wjd.124565

Yang FZ, Li HY, Li G, Zhang YL, Ji Q. Cluster analysis of computed tomography identifies duration-associated abdominal fat deposition in type 2 diabetes mellitus. World J Diabetes 2026; 17(11): 124565 [DOI: 10.4239/wjd.124565]

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