Association between estimated glucose disposal rate and metabolic dysfunction-associated steatotic liver disease in type 2 diabetes mellitus patients

doi:10.4239/wjd.125355

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 17, Issue 10

This Article

(4)

(0)

(78)

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Diabetes

ISSN

1948-9358

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Observational Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Diabetes. Oct 15, 2026; 17(10): 125355
Published online Oct 15, 2026. doi: 10.4239/wjd.125355

Table 1 Comparison of baseline clinical characteristics in type 2 diabetes mellitus patients, n (%)/mean ± SD

Variables	Total (n = 648)	Non-MASLD (n = 380)	MASLD (n = 260)	P value
Age (year)	57.19 ± 13.07	60.68 ± 11.79	52.25 ± 13.23	< 0.001
Duration (year)	5.00 (2.00, 14.00)	8.00 (2.75, 15.00)	3.00 (1.00, 9.25)	< 0.001
SBP (mmHg)	139.68 ± 18.44	139.37 ± 19.41	140.10 ± 16.98	0.611
DBP (mmHg)	82.89 ± 12.36	80.77 ± 11.96	85.88 ± 12.31	< 0.001
BMI (kg/m²)	26.41 ± 4.51	25.11 ± 3.76	28.26 ± 4.84	< 0.001
WC (cm)	96.44 ± 12.15	93.33 ± 11.16	100.85 ± 12.16	< 0.001
HC (cm)	102.25 ± 10.28	99.88 ± 8.95	105.60 ± 11.09	< 0.001
LDL-C (mmol/L)	3.09 ± 0.94	3.03 ± 0.92	3.19 ± 0.96	0.034
HDL-C (mmol/L)	1.23 ± 0.30	1.26 ± 0.29	1.19 ± 0.31	0.003
TG (mmol/L)	2.20 ± 2.65	1.81 ± 2.28	2.74 ± 3.03	< 0.001
TC (mmol/L)	4.95 ± 1.38	4.80 ± 1.29	5.17 ± 1.48	0.001
ALT (U/L)	23.00 (16.00, 35.00)	19.00 (14.00, 28.25)	29.00 (20.00, 45.00)	< 0.001
AST (U/L)	19.00 (15.00, 26.00)	17.00 (14.00, 22.00)	22.00 (17.00, 33.00)	< 0.001
FBG (mmol/L)	9.37 ± 3.36	9.14 ± 3.51	9.69 ± 3.11	0.043
HbA1c (%)	8.64 ± 2.06	8.58 ± 2.17	8.73 ± 1.89	0.367
BUN (mmol/L)	5.69 ± 2.44	5.77 ± 2.08	5.56 ± 2.87	0.273
UA (mmol/L)	341.55 ± 101.79	325.64 ± 95.85	364.10 ± 105.81	< 0.001
Scr (mmol/L)	64.88 ± 24.26	65.53 ± 25.09	63.96 ± 23.05	0.416
Hcy (μmol/L)	14.17 ± 7.35	13.74 ± 6.23	14.76 ± 8.67	0.082
RBC (× 10¹²/L)	4.66 ± 0.58	4.56 ± 0.59	4.80 ± 0.52	< 0.001
Hb (g/L)	142.18 ± 19.37	138.74 ± 19.37	147.05 ± 18.32	< 0.001
WBC (× 10⁹/L)	6.20 ± 1.86	5.98 ± 1.69	6.51 ± 2.04	< 0.001
PLT (× 10⁹/L)	224.57 ± 60.02	218.11 ± 58.58	233.73 ± 60.95	0.001
eGDR	5.85 ± 2.46	6.30 ± 2.43	5.21 ± 2.36	< 0.001
Sex	-	-	-	0.025
Male	375 (57.87)	206 (54.21)	169 (63.06)	-
Female	273 (42.13)	174 (45.79)	99 (36.94)	-
Smoking	-	-	-	0.362
No	200 (30.86)	112 (29.47)	88 (32.84)	-
Yes	448 (69.14)	268 (70.53)	180 (67.16)	-
HT	-	-	-	0.030
No	289 (44.60)	183 (48.16)	106 (39.55)	-
Yes	359 (55.40)	197 (51.84)	162 (60.45)	-
eGDR quantile	-	-	-	< 0.001
Q1	162 (25.00)	65 (17.11)	97 (36.19)	-
Q2	162 (25.00)	99 (26.05)	63 (23.51)	-
Q3	162 (25.00)	101 (26.58)	61 (22.76)	-
Q4	162 (25.00)	115 (30.26)	47 (17.54)	-

BMI: Body mass index; SBP: Systolic blood pressure; DBP: Diastolic blood pressure; WC: Waist circumference; HC: Hip circumference; HbA1c: Glycated hemoglobin; BUN: Blood urea nitrogen; Scr: Serum creatinine; UA: Uric acid; TC: Total cholesterol; TG: Triglyceride; HDL-C: High-density lipoprotein cholesterol; LDL-C: Low-density lipoprotein cholesterol; FBG: Fasting blood glucose; ALT: Alanine aminotransferase; AST: Aspartate transaminase; Hcy: Homocysteine; RBC: Red blood cell; WBC: White blood cell; Hb: Hemoglobin; PLT: Platelet; HT: Hypertension; eGDR: Estimated glucose disposal rate; MASLD: Metabolic dysfunction-associated steatotic liver disease.

Full Size Table

Citation: Yin JT, Lu YX, Li ZM, Niu S. Association between estimated glucose disposal rate and metabolic dysfunction-associated steatotic liver disease in type 2 diabetes mellitus patients. World J Diabetes 2026; 17(10): 125355
URL: https://www.wjgnet.com/1948-9358/full/v17/i10/125355.htm
DOI: https://dx.doi.org/10.4239/wjd.125355

Yin JT, Lu YX, Li ZM, Niu S. Association between estimated glucose disposal rate and metabolic dysfunction-associated steatotic liver disease in type 2 diabetes mellitus patients. World J Diabetes 2026; 17(10): 125355 [DOI: 10.4239/wjd.125355]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.