Hypertriglyceridemic acute pancreatitis with diabetes mellitus: Investigation of factors and predictive models for severity progression

doi:10.4239/wjd.124186

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Diabetes. Oct 15, 2026; 17(10): 124186
Published online Oct 15, 2026. doi: 10.4239/wjd.124186

Table 3 Analysis of risk factors for progression to severe disease in patients

Variables	Univariate logistic regression			Multivariate logistic regression
Variables	OR	95%CI	P value	OR	95%CI	P value
HR	1.04	1.02-1.06	< 0.001^a	1.03	1.01-1.05	0.027^a
RR	1.07	1.01-1.12	0.012^a	-	-	-
BMI	1.12	1.02-1.23	0.023^a	1.14	0.97-1.33	0.106
NLR	1.08	1.01-1.16	0.034^a	-	-	-
PLT	0.99	0.98-0.99	< 0.001^a	0.99	0.98-0.99	< 0.001^a
PT	1.54	1.15-2.07	0.004^a	0.69	0.43-1.1	0.120
ALB	0.91	0.87-0.96	< 0.001^a	0.91	0.84-0.98	0.019^a
CRP	1.01	1.01-1.01	0.009^a	-	-	-
PCT	1.16	1.06-1.26	< 0.001^a	-	-	-
Cr	1.02	1.01-1.03	< 0.001^a	-	-	-
Ca²⁺	0.08	0.03-0.25	< 0.001^a	0.26	0.06-1.02	0.053
TG	1.02	0.99-1.05	0.144	-	-	-
AMY	1.00	1.00-1.00	0.386	-	-	-
LPS	1.01	1.01-1.01	0.004^a	1.01	1.01-1.01	0.014^a
FPG	1.12	1.03-1.21	0.007^a	-	-	-
RPG	1.20	1.09-1.31	< 0.001^a	1.22	1.07-1.39	0.003^a
Pleural effusion	4.69	2.23-9.86	< 0.001^a	3.83	1.30-11.25	0.015^a

^aIndicate that results are statistically significant.

OR: Odds ratio; CI: Confidence interval; HR: Heart rate; RR: Respiratory rate; BMI: Body mass index; NLR: Neutrophil-to-lymphocyte ratio; PLT: Platelet; PT: Prothrombin time; ALB: Albumin; CRP: C-reactive protein; PCT: Procalcitonin; Cr: Creatinine; TG: Triglyceride; AMY: Serum amylase; LPS: Serum lipase; FPG: Fasting plasma glucose; RPG: Random plasma glucose.

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Citation: Chai M, Zhao LX, Wang ZG, Xu DH. Hypertriglyceridemic acute pancreatitis with diabetes mellitus: Investigation of factors and predictive models for severity progression. World J Diabetes 2026; 17(10): 124186
URL: https://www.wjgnet.com/1948-9358/full/v17/i10/124186.htm
DOI: https://dx.doi.org/10.4239/wjd.124186

Chai M, Zhao LX, Wang ZG, Xu DH. Hypertriglyceridemic acute pancreatitis with diabetes mellitus: Investigation of factors and predictive models for severity progression. World J Diabetes 2026; 17(10): 124186 [DOI: 10.4239/wjd.124186]

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