Regression to normoglycemia, progression to diabetes, and their association with health outcomes in Chinese adults with untreated prediabetes

Table 2 Binary logistic regression analysis of the factors associated with regression to normoglycemia and progression to diabetes from prediabetes

Factors	Regression to normoglycemia		Progression to diabetes
	Adjusted OR (95%CI)a	P value	Adjusted OR (95%CI)a	P value
Age (≥ 60 vs < 60)	0.67 (0.54-0.83)	< 0.001	1.10 (0.86-1.40)	0.468
Male vs female	1.58 (1.23-2.03)	< 0.001	0.76 (0.55-1.03)	0.079
High school or above vs middle school or below	1.29 (0.92-1.81)	0.137	0.95 (0.60-1.48)	0.839
Married vs other	1.04 (0.78-1.41)	0.780	0.84 (0.61-1.16)	0.281
Total household income (≥ 10000 vs < 10000, CNY)	0.89 (0.69-1.16)	0.390	0.87 (0.65-1.17)	0.352
Health insurance (yes vs no)	0.71 (0.46-1.12)	0.128	1.19 (0.66-2.30)	0.585
Current smoker vs others	0.79 (0.60-1.04)	0.089	1.29 (0.93-1.81)	0.129
Current alcohol drinker vs other	0.94 (0.71-1.24)	0.669	0.99 (0.69-1.41)	0.971
Active physical activity vs other	0.89 (0.72-1.10)	0.282	0.83 (0.65-1.06)	0.135
Disease status (yes vs no)
Hypertension	1.19 (0.94-1.50)	0.156	1.56 (1.21-2.02)	0.001
CVD	0.97 (0.71-1.32)	0.865	1.27 (0.93-1.74)	0.132
Dyslipidemia	0.96 (0.66-1.36)	0.810	1.72 (1.23-2.40)	0.001
Number of comorbidities (≥ 1 vs 0)	1.16 (0.94-1.44)	0.166	1.23 (0.96-1.58)	0.101
BMI (≥ 24 kg/m2 vs < 24 kg/m2)	0.78 (0.61-0.98)	0.033	1.78 (1.36-2.32)	< 0.001
Self-reported general health (very good/good/fair vs poor/very poor)	0.95 (0.75-1.22)	0.693	0.89 (0.68-1.18)	0.414
High-sensitivity C-reactive protein (every 1-mg/L increase)	0.98 (0.95-1.00)	0.075	1.01 (0.99-1.02)	0.209

^aAll the factors listed in this table were adjusted for.

CNY: Chinese yuan; CVD: Cardiovascular disease; BMI: Body mass index; OR: Odds ratio.