Combined effects of glycemic status and adiposity on cardiovascular risk in chronic kidney disease: A nationwide population-based study

Table 4 Multivariate cox analysis for incident cardiovascular outcome by diabetes mellitus status

Outcome	DM status	n	Events (n)	Duration, PY	IR, per 1000	Adjusted HR (95%CI)
						Model 1	Model 2	Model 3
CVD	Normal	857846	47590	6508730.39	7.31	1 (reference)	1 (reference)	1 (reference)
	IFG	457410	32092	3393918.30	9.46	1.30 (1.28-1.32)	1.07 (1.05-1.08)	1.04 (1.03-1.06)
	DM	399603	48151	2824691.28	17.05	2.35 (2.32-2.38)	1.69 (1.67-1.72)	1.57 (1.55-1.59)
MI	Normal	857846	22657	6586843.49	3.44	1 (reference)	1 (reference)	1 (reference)
	IFG	457410	15083	3446873.19	4.38	1.28 (1.25-1.30)	1.06 (1.04-1.09)	1.05 (1.02-1.07)
	DM	399603	23193	2901757.43	7.99	2.35 (2.30-2.39)	1.73 (1.70-1.76)	1.60 (1.57-1.63)
Stroke	Normal	857846	27725	6568204.74	4.22	1 (reference)	1 (reference)	1 (reference)
	IFG	457410	19065	3433118.71	5.55	1.32 (1.30-1.34)	1.07 (1.05-1.09)	1.05 (1.03-1.07)
	DM	399603	28972	2881142.97	10.06	2.40 (2.36-2.44)	1.70 (1.67-1.73)	1.58 (1.56-1.61)
Death	Normal	857846	66149	6652038.98	9.94	1 (reference)	1 (reference)	1 (reference)
	IFG	457410	45975	3490148.71	13.17	1.33 (1.32-1.35)	1.03 (1.02-1.04)	1.03 (1.02-1.05)
	DM	399603	70520	2965646.58	23.78	2.41 (2.39-2.44)	1.61 (1.60-1.63)	1.60 (1.58-1.62)

Model 1: Non-adjusted; Model 2: Adjusted for age, sex; Model 3: Adjusted for model 2 plus smoking, alcohol drinking, regular exercise, income, hypertension, dyslipidemia. 95%CI: 95% confidence interval; CVD: Cardiovascular disease; MI: Myocardial infarction; DM: Diabetes mellitus; IFG: Impaired fasting glucose; PY: Person years; IR: Incidence rate; HR: Hazard ratio.