Microtubule affinity-regulating kinase 4 exacerbates diabetic cardiomyopathy by inhibiting UNC-51-like kinase 1-mediated mitochondrial autophagy

Figure 1 Microtubule affinity-regulating kinase 4 was upregulated in diabetic cardiomyopathy models. A and B: Microtubule affinity-regulating kinase 4 protein levels in diabetic cardiomyopathy model mice; C and D: Microtubule affinity-regulating kinase 4 protein levels in cardiomyocytes stimulated with 200 μM palmitic acid and 33.3 mmol/L glucose. Values are mean ± SD (n = 4). ^aP < 0.05, and ^bP < 0.01. Con: Control; DCM: Diabetic cardiomyopathy; MARK4: Microtubule affinity-regulating kinase 4; GAPDH: Glyceraldehyde 3-phosphate dehydrogenase; HG: High glucose.