Association of serum and vitreous homocysteine and uric acid concentrations with post-vitrectomy prognosis in patients with proliferative diabetic retinopathy

Table 5 Correlation analysis of vitreous homocysteine and uric acid with optical coherence tomography angiography parameters within the proliferative diabetic retinopathy group (n = 44)

Variables	Time	Vitreous Hcy (μmol/L)		Vitreous UA (μmol/L)
		Pearson	P value	Pearson	P value
SCP length density (mm-1)
Superior	7 days	0.015	0.927	0.18	0.261
	30 days	-0.025	0.882	-0.179	0.288
	90 days	0.021	0.898	0.021	0.9
Inferior	7 days	-0.15	0.348	-0.089	0.581
	30 days	-0.013	0.941	0.246	0.143
	90 days	-0.059	0.72	0.018	0.915
Nasal	7 days	-0.063	0.697	0.133	0.407
	30 days	0.255	0.128	-0.413	0.011a
	90 days	-0.058	0.726	0.141	0.392
Temporal	7 days	-0.199	0.212	-0.114	0.476
	30 days	0.06	0.725	0.178	0.292
	90 days	-0.101	0.542	-0.163	0.323
Fovea	7 days	-0.084	0.604	0.066	0.681
	30 days	0.132	0.443	-0.232	0.174
	90 days	-0.22	0.183	-0.009	0.959
Inner ring	7 days	-0.199	0.213	-0.106	0.51
	30 days	0.024	0.883	0.252	0.108
	90 days	-0.196	0.22	-0.013	0.935
Full area	7 days	-0.158	0.307	0.221	0.15
	30 days	-0.01	0.949	0.195	0.215
	90 days	-0.12	0.941	0.1	0.543
SCP width density (mm-2)
Superior	7 days	-0.255	0.108	0.032	0.84
	30 days	-0.006	0.974	-0.083	0.624
	90 days	0.006	0.973	-0.005	0.978
Inferior	7 days	-0.303	0.014a	0.00	1.00
	30 days	0.032	0.85	0.057	0.737
	90 days	-0.07	0.67	-0.009	0.957
Nasal	7 days	-0.157	0.326	0.134	0.405
	30 days	0.18	0.287	0.313	0.06
	90 days	0.027	0.869	-0.007	0.967
Temporal	7 days	-0.237	0.136	0.134	0.403
	30 days	0.278	0.096	-0.391a	0.017a
	90 days	0.143	0.385	-0.205	0.21
Fovea	7 days	-0.238	0.134	0.026	0.874
	30 days	-0.074	0.662	-0.109	0.522
	90 days	-0.096	0.56	-0.015	0.93
Inner ring	7 days	-0.291	0.065	-0.067	0.667
	30 days	-0.151	0.372	-0.341	0.039a
	90 days	0.136	0.408	0.197	0.23
Full area	7 days	-0.3	0.057	-0.073	0.651
	30 days	0.139	0.412	0.315	0.057
	90 days	-0.001	0.997	0.115	0.485
FAZ
FAZ (mm2)	7 days	-0.157	0.326	-0.008	0.959
	30 days	0.177	0.294	0.134	0.428
	90 days	0.343a	0.032a	0.041	0.803
The perimeter of FAZ (mm)	7 days	-0.158	0.325	-0.108	0.503
	30 days	0.084	0.621	-0.013	0.941
	90 days	0.208	0.204	0.03	0.858

^aP < 0.05.

Hcy: Homocysteine; UA: Uric acid; OCTA: Optical coherence tomography angiography; SCP: Superficial capillary plexus; FAZ: Foveal avascular zone.