Association of serum and vitreous homocysteine and uric acid concentrations with post-vitrectomy prognosis in patients with proliferative diabetic retinopathy

Table 4 Correlation analysis of vitreous homocysteine, uric acid, and best-corrected visual acuity, optical coherence tomography parameters within the proliferative diabetic retinopathy group (n = 44)

Variables	Time	Vitreous Hcy (μmol/L)		Vitreous UA (μmol/L)
		Pearson	P value	Pearson	P value
BCVA (logMAR)	1 day	0.594	0.006a	-0.064	0.787
	7 days	0.261	0.113	0.027	0.871
	30 days	0.156	0.448	-0.086	0.676
	90 days	0.264	0.361	0.093	0.753
pRNFL
Optic daysisc	7 days	-0.164	0.354	-0.107	0.548
	30 days	-0.149	0.440	-0.102	0.597
	90 days	-0.382	0.054	-0.297	0.141
Temporal	7 days	-0.105	0.553	-0.046	0.794
	30 days	0.032	0.869	0.057	0.771
	90 days	-0.085	0.631	-0.376	0.058
Superior temporal	7 days	-0.029	0.866	-0.216	0.199
	30 days	0.046	0.804	-0.243	0.180
	90 days	-0.399	0.036a	-0.285	0.142
Inferior temporal	7 days	-0.155	0.361	-0.055	0.745
	30 days	-0.039	0.818	0.053	0.754
	90 days	-0.057	0.747	-0.042	0.812
Nasal	7 days	0.112	0.530	-0.033	0.852
	30 days	-0.113	0.559	-0.132	0.494
	90 days	-0.107	0.603	-0.131	0.523
Superior nasal	7 days	0.118	0.506	-0.002	0.993
	30 days	0.179	0.353	0.032	0.871
	90 days	-0.054	0.761	-0.058	0.743
Inferior nasal	7 days	-0.354	0.043a	0.177	0.323
	30 days	-0.268	0.160	0.065	0.737
	90 days	-0.716	< 0.001a	-0.343	0.086
CMT and SFCT
CMT	7 days	-0.105	0.531	-0.078	0.642
	30 days	-0.114	0.526	-0.043	0.812
	90 days	-0.166	0.400	-0.085	0.669
SFCT	7 days	-0.023	0.894	-0.059	0.727
	30 days	-0.059	0.726	-0.210	0.248
	90 days	-0.012	0.953	-0.080	0.693

^aP < 0.05.

Hcy: Homocysteine; UA: Uric acid; BCVA: Best-corrected visual acuity; LogMAR: Logarithmic minimum angle of resolution; OCT: Optical coherence tomography angiography; pRNFL: Peripapillary retinal nerve fiber layer; CMT: Central macular thickness; SFCT: Subfoveal choroid thickness.