Endothelial cell-derived exosomes inhibit high glucose-induced osteoblast ferroptosis by activating microRNA-335-3p/prostaglandin endoperoxide synthase 2

doi:10.4239/wjd.v17.i1.111165

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Jan 15, 2026; 17(1): 111165
Published online Jan 15, 2026. doi: 10.4239/wjd.v17.i1.111165

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Figure 1 Endothelial cell-exosomes identification and uptake. A: Transmission electron microscopy, orange arrows indicate exosomes; B: Nanoparticle tracking analysis for exosome size distribution; C: Western blotting for detection of exosomes surface markers; D: Exosome phagocytosis experiment. ECs: Endothelial cells; EC-Exos: Endothelial cell-exosomes.

Citation: Shao C, Zhang LJ, Song YL, Wang YQ, Zha XJ, Li J, Ye CS, Chen LL, Chen MW, Jin GX. Endothelial cell-derived exosomes inhibit high glucose-induced osteoblast ferroptosis by activating microRNA-335-3p/prostaglandin endoperoxide synthase 2. World J Diabetes 2026; 17(1): 111165
URL: https://www.wjgnet.com/1948-9358/full/v17/i1/111165.htm
DOI: https://dx.doi.org/10.4239/wjd.v17.i1.111165

Shao C, Zhang LJ, Song YL, Wang YQ, Zha XJ, Li J, Ye CS, Chen LL, Chen MW, Jin GX. Endothelial cell-derived exosomes inhibit high glucose-induced osteoblast ferroptosis by activating microRNA-335-3p/prostaglandin endoperoxide synthase 2. World J Diabetes 2026; 17(1): 111165 [PMID: 41608100 DOI: 10.4239/wjd.v17.i1.111165]

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