Indirect bilirubin is inversely associated with diabetic retinopathy risk and is a potential predictive biomarker

Figure 3 Receiver operating characteristic analysis of the association between indirect bilirubin and the risk of developing diabetic retinopathy. Receiver operating characteristic (ROC) curve analysis was carried out to determine the cutoff point of indirect bilirubin (IBIL) for predicting the risk of developing diabetic retinopathy (DR). Statistical significance was determined at a P value < 0.05. a: ROC analysis of IBIL for predicting the risk of developing DR in patients with type 2 diabetes mellitus (T2DM); b: ROC analysis of IBIL for predicting the risk of developing DR in male T2DM patients with elevated diastolic blood pressure. AUC: Area under the curve.