©The Author(s) 2025.
World J Diabetes. Sep 15, 2025; 16(9): 107517
Published online Sep 15, 2025. doi: 10.4239/wjd.v16.i9.107517
Published online Sep 15, 2025. doi: 10.4239/wjd.v16.i9.107517
Table 3 Advantages and disadvantages of replacing the term “type 2 diabetes mellitus” with “metabolic dysfunction associated hyperglycemic disease”
| Advantages of updating to MAHD | Limitations/ arguments |
| The new terminology reflects the pathophysiological basis of the disease | Terms “associated disease” and “metabolic dysfunction” lack clear and standardized definitions |
| The new terminology (AMAD and MAHD) echoes with the existing terminology with similar pathophysiological mechanisms. e.g., Metabolic dysfunction associated fatty liver diseases | |
| The new terminology is honest and transparent of the major pathophysiological mechanism, thereby providing clarity in care | The new terminology simply exchanges one form of stigma (sugar-related) for another (weight-related) |
| It groups all the currently considered different diseases with the same pathology into an umbrella of a single disease | |
| It helps in early diagnosis of other components of AMAD | |
| It helps multidisciplinary collaboration and holistic care | |
| It conveys a message of hope and empowerment, reinforcing the idea that early intervention can halt or even reverse the course of the disease | |
| It reflects the interconnections between various metabolic disease and CVD, CKD, necessitating early screening for associated problems | |
| It emphasizes the central role of lifestyle medicine in the promotion of overall health from multiple diseases due to excess fat accumulation | |
| It helps to differentiate other types of diabetes with different pathophysiological mechanisms into different categories |
- Citation: Raveendran AV. Type 2 diabetes mellitus: Isn’t it time to update the terminology? World J Diabetes 2025; 16(9): 107517
- URL: https://www.wjgnet.com/1948-9358/full/v16/i9/107517.htm
- DOI: https://dx.doi.org/10.4239/wjd.v16.i9.107517