Albuminuria is independently associated with preclinical left ventricular systolic dysfunction: The TESEO study

doi:10.4239/wjd.v16.i9.106914

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Sep 15, 2025; 16(9): 106914
Published online Sep 15, 2025. doi: 10.4239/wjd.v16.i9.106914

Table 4 Echocardiografic parameters of 193 type 2 diabetes subjects stratified by class of albuminuria, mean ± SD

Characteristics	Normoalbuminuria (n = 168)	Albuminuria (n = 25)	P value
Structural parameters
LVMi (mL/m²)	87.80 ± 17.09	94.36 ± 26.08	0.074
IVS (mm)	11.03 ± 1.42	11.00 ± 1.47	0.915
PW (mm)	10.33 ± 1.18	10.60 ± 1.56	0.302
RWT	0.47 ± 0.07	0.46 ± 0.07	0.623
EDV/BSA	48.90 ± 9.81	46.92 ± 12.47	0.366
LVH (%)	17.3	24.0	0.415
Diastolic function
Lateral e’ (cm/seconds)	10.18 ± 2.42	10.57 ± 3.53	0.504
E/e’ average	7.78 ± 2.30	8.15 ±2.69	0.482
LAVI (mL/m²)	31.20 ± 7.16	30.19 ± 10.79	0.541
Systolic function
EF (%)	61.29 ± 3.76	61.36 ± 3.72	0.932
GLS	-19.88 ± 2.16	-18.29 ± 2.99	0.001

LVMi: Left ventricle mass index; IVS: Interventricular septum; PW: Posterior wall; RWT: Relative wall thickness; EDV: End-diastolic volume; BSA: Body surface area; LVH: Left ventricular hypertrophy; e’: Mitral annulus velocity; E/e’: E-wave/mitral annulus velocity; LAVI: Left atrial volume index; EF: Ejection fraction; GLS: Global longitudinal strain.

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Citation: Barutta F, Andreis A, Bellettini M, Beccuti G, Ferro A, Bollati M, Bellini S, Gioiello G, Mengozzi G, De Ferrari GM, Alunni G, Broglio F, Gruden G. Albuminuria is independently associated with preclinical left ventricular systolic dysfunction: The TESEO study. World J Diabetes 2025; 16(9): 106914
URL: https://www.wjgnet.com/1948-9358/full/v16/i9/106914.htm
DOI: https://dx.doi.org/10.4239/wjd.v16.i9.106914

Barutta F, Andreis A, Bellettini M, Beccuti G, Ferro A, Bollati M, Bellini S, Gioiello G, Mengozzi G, De Ferrari GM, Alunni G, Broglio F, Gruden G. Albuminuria is independently associated with preclinical left ventricular systolic dysfunction: The TESEO study. World J Diabetes 2025; 16(9): 106914 [PMID: 40980294 DOI: 10.4239/wjd.v16.i9.106914]

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