Albuminuria is independently associated with preclinical left ventricular systolic dysfunction: The TESEO study

doi:10.4239/wjd.v16.i9.106914

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Sep 15, 2025; 16(9): 106914
Published online Sep 15, 2025. doi: 10.4239/wjd.v16.i9.106914

Table 3 Echocardiografic parameters of 193 type 2 diabetes subjects stratified by global longitudinal strain-left ventricular systolic dysfunction status, mean ± SD

Characteristics	GLS < -18 (n = 151)	GLS ≥ -18% (n = 42)	P value
Structural parameters
LVMi (mL/m²)	87.94 ± 18.24	89.57 ± 18.10	0.608
IVS (mm)	11.02 ± 1.32	11.07 ± 1.764	0.826
PW (mm)	10.34 ± 1.19	10.43 ± 1.38	0.696
RWT	0.47 ± 0.69	0.46 ± 0.79	0.687
EDV/BSA	48.79 ± 9.56	48.13 ± 12.3	0.715
LVH (%)	17.9	19.0	0.862
Diastolic function
Lateral e’ (cm/seconds)	10.36 ± 2.60	9.72 ± 2.43	0.175
E/e’ average	7.71 ± 2.31	8.25 ± 2.48	0.202
LAVI (mL/m²)	31.30 ± 7.31	30.35 ± 8.999	0.435
Systolic function
EF (%)	61.74 ± 3.51	59.74 ± 4.19	0.002

GLS: Global longitudinal strain; LVMi: Left ventricle mass index; IVS: Interventricular septum; PW: Posterior wall; RWT: Relative wall thickness; EDV: End-diastolic volume; BSA: Body surface area; LVH: Left ventricular hypertrophy; e’: Mitral annulus velocity; E/e’: E-wave/mitral annulus velocity; LAVI: Left atrial volume index; EF: Ejection fraction.

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Citation: Barutta F, Andreis A, Bellettini M, Beccuti G, Ferro A, Bollati M, Bellini S, Gioiello G, Mengozzi G, De Ferrari GM, Alunni G, Broglio F, Gruden G. Albuminuria is independently associated with preclinical left ventricular systolic dysfunction: The TESEO study. World J Diabetes 2025; 16(9): 106914
URL: https://www.wjgnet.com/1948-9358/full/v16/i9/106914.htm
DOI: https://dx.doi.org/10.4239/wjd.v16.i9.106914

Barutta F, Andreis A, Bellettini M, Beccuti G, Ferro A, Bollati M, Bellini S, Gioiello G, Mengozzi G, De Ferrari GM, Alunni G, Broglio F, Gruden G. Albuminuria is independently associated with preclinical left ventricular systolic dysfunction: The TESEO study. World J Diabetes 2025; 16(9): 106914 [PMID: 40980294 DOI: 10.4239/wjd.v16.i9.106914]

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