Increased tumor necrosis factor-receptor superfamily plasma levels are associated with early renal or retinal involvement in intermediate hyperglycemia

doi:10.4239/wjd.v16.i9.106002

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Sep 15, 2025; 16(9): 106002
Published online Sep 15, 2025. doi: 10.4239/wjd.v16.i9.106002

Table 4 The statistical significance of the variables associated with presence of retinopathy

Variables	P value	FDR adjusted
TIM-3 (pg/mL)	7.10 × 10^-6	0.0001023
Gal3 (pg/mL)	1.02 × 10^-5	0.0001229
TNF-R1 (pg/mL)	0.00012715	0.0013078
TNF-R2 (pg/mL)	0.00093481	0.0084133
Glucose > 155mg/dL at 1 hour	0.057532
C-reactive protein	0.058425

FDR: False discovery rate; TIM-3: T-cell immunoglobulin and mucin domain 3; TNF-R2: Tumor necrosis factor receptor 2; Gal3: Galectin-3; TNF-R1: Tumor necrosis factor receptor 1.

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Citation: Mas-Fontao S, Civantos E, Boukichou-Abdelkader N, Moreno JA, Gomez-Guerrero C, Gálvez MIL, Tuomilehto J, Lind M, Gabriel R, Egido J. Increased tumor necrosis factor-receptor superfamily plasma levels are associated with early renal or retinal involvement in intermediate hyperglycemia. World J Diabetes 2025; 16(9): 106002
URL: https://www.wjgnet.com/1948-9358/full/v16/i9/106002.htm
DOI: https://dx.doi.org/10.4239/wjd.v16.i9.106002

Mas-Fontao S, Civantos E, Boukichou-Abdelkader N, Moreno JA, Gomez-Guerrero C, Gálvez MIL, Tuomilehto J, Lind M, Gabriel R, Egido J. Increased tumor necrosis factor-receptor superfamily plasma levels are associated with early renal or retinal involvement in intermediate hyperglycemia. World J Diabetes 2025; 16(9): 106002 [PMID: 40980291 DOI: 10.4239/wjd.v16.i9.106002]

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