Increased tumor necrosis factor-receptor superfamily plasma levels are associated with early renal or retinal involvement in intermediate hyperglycemia

Table 1 Summary of the statistical significance of the variables associated with hyperfiltration, with corresponding P values and false discovery rate-adjusted values

Variables	P value	FDR
IL-6 (pg/mL)	8.81 × 10-18	6.35 × 10-16
TIM-3 (pg/mL)	2.10 × 10-5	0.00066
TNF-R2 (pg/mL)	2.37 × 10-5	0.0006
Gal3 (pg/mL)	0.0001	0.0029
TNF-R1 (pg/mL)	0.0002	0.0035
ALT (UI/L)	0.0130
Disposition index	0.0253
Triglycerides (mmol/L)	0.0484

FDR: False discovery rate; IL-6: Interleukin-6; TIM-3: T-cell immunoglobulin and mucin domain 3; TNF-R2: Tumor necrosis factor receptor 2; Gal3: Galectin-3; TNF-R1: Tumor necrosis factor receptor 1; ALT: Alanine aminotransferase. Bonferroni threshold for our study is P > 0.0007.