Gut dysbiosis, low-grade inflammation, and renal impairment severity in elderly diabetic nephropathy

Table 3 Comparison of relative abundance of gut microbiota between diabetic nephropathy group and control group

Variables	DN group (n = 167)	Control group (n = 85)	t	P value
Bacteroides (%)	18.44 ± 3.64	21.76 ± 3.69	-6.811	0.000
Fusobacterium (%)	7.88 ± 2.13	4.00 ± 1.58	14.883	0.000
Blautia (%)	8.37 ± 1.12	8.59 ± 1.10	-1.487	0.138
Bifidobacterium (%)	2.09 ± 0.55	4.30 ± 0.88	-24.326	0.000
Prevotella (%)	3.42 ± 0.39	3.46 ± 0.46	-0.725	0.469
‌Alloprevotella (%)	2.59 ± 0.39	2.60 ± 0.42	-0.124	0.901
Lachnospira (%)‌	2.35 ± 0.49	2.52 ± 0.48	-2.697	0.007
Roseburia (%)	2.37 ± 0.44	2.29 ± 0.35	1.378	0.170
Butyricimonas (%)	5.46 ± 0.84	5.87 ± 0.39	-1.500	0.135
Escherichia-Shigella (%)	1.40 ± 0.30	1.44 ± 0.29	-1.085	0.279
Klebsiella (%)	4.22 ± 0.30	2.51 ± 0.33	42.544	0.000
Enterococcus (%)	3.91 ± 0.42	2.39 ± 0.19	31.516	0.000
Veillonella (%)	2.87 ± 0.57	2.23 ± 0.39	9.321	0.000
Megamonas (%)	2.33 ± 0.51	1.68 ± 0.29	10.766	0.000

DN: Diabetic nephropathy.