Identification and mechanistic insights of ubiquitin-proteasome system and pyroptosis-related biomarkers in type 2 diabetes mellitus

doi:10.4239/wjd.v16.i8.104879

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Aug 15, 2025 (publication date) through Aug 17, 2025

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Aug 15, 2025; 16(8): 104879
Published online Aug 15, 2025. doi: 10.4239/wjd.v16.i8.104879

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Figure 4 Immune infiltration analysis. A and B: Comparison of immune cell scores between type 2 diabetes mellitus (T2DM) and normal control groups in training set and validation set; C and D: Correlation of biomarkers to differential immune cells in training set and validation set. The color and size of the irregular shapes in the figure represent the size of the correlation. ^aP < 0.05; ^bP < 0.01; ^cP < 0.001; ^dP < 0.0001. MDSC: Myeloid-derived suppressor cell.

Citation: Yuan XJ, Zhang ZC, Li J, Ye SD, Zhou W. Identification and mechanistic insights of ubiquitin-proteasome system and pyroptosis-related biomarkers in type 2 diabetes mellitus. World J Diabetes 2025; 16(8): 104879
URL: https://www.wjgnet.com/1948-9358/full/v16/i8/104879.htm
DOI: https://dx.doi.org/10.4239/wjd.v16.i8.104879