Prognostic value of microRNA-495-3p, adiponectin, and cardiometabolic index in type 2 diabetic nephropathy

Table 6 The predictive value of serum microRNA-495-3p, adiponectin, cardiometabolic index, alanine aminotransferase, aspartate aminotransferase, urea nitrogen, and serum creatinine levels for poor prognosis of patients

Variable	AUC	Cut-off value	95%CI		Sensitivity	Specificity	P value
			Lower limit	Upper limit
ADPN	0.902	12.675	0.837	0.967	0.919	0.770	< 0.001
CMI	0.757	0.965	0.650	0.863	0.622	0.869	< 0.001
miR-495-3p	0.762	0.525	0.657	0.867	0.622	0.885	< 0.001
Alanine aminotransferase	0.899	45.320	0.828	0.970	0.973	0.852	< 0.001
Aspartate aminotransferase	0.852	54.150	0.755	0.949	0.811	0.951	< 0.001
Urea nitrogen	0.916	13.990	0.842	0.990	0.946	0.951	< 0.001
Serum creatinine	0.910	45.380	0.847	0.973	0.919	0.902	< 0.001

AUC: Area under the curve; CI: Confidence interval; miR-495-3p: microRNA-495-3p; ADPN: Adiponectin; CMI: Cardiometabolic index.