Impact of intensive insulin therapy on dynamic cardiac function in critically ill patients with stress-induced hyperglycemia

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Jul 15, 2025 (publication date) through Jul 28, 2025

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Jul 15, 2025; 16(7): 107767
Published online Jul 15, 2025. doi: 10.4239/wjd.v16.i7.107767

Table 3 Comparison of intensive care unit stay and clinical outcomes among three groups, n (%)

Group	ICU stay (mean ± SD)	P value	Ventilator use	P value	Mechanical ventilation time (mean ± SD, h)	P value	Mortality	P value
Conventional treatment group (n = 50)	14.5 ± 2.60^a	< 0.001 vs normal	38 (76.0)^a	< 0.001 vs normal	121.8 ± 15.8^a	< 0.001 vs normal	21 (42.0)^a	< 0.001 vs normal
Intensive insulin therapy group (n = 51)	10.3 ± 3.40^a^,^b	< 0.001 vs normal; < 0.001 vs conv.	29 (56.9)^a^,^b	0.0003 vs normal; 0.0419 vs conv.	82.6 ± 13.2^a^,^b	< 0.001 vs normal; < 0.001 vs conv.	12 (23.5)^a^,^b	0.0061 vs normal; 0.0478 vs conv.
Normal glycemia group (n = 85)	7.3 ± 3.74	-	22 (25.9)	-	59.5 ± 11.0	-	6 (7.1)	-

^aP < 0.05 vs the normal glycemia group.

^bP < 0.05 vs the conventional therapy group.

ICU: Intensive care unit.

Citation: Wang YD, Yu JJ. Impact of intensive insulin therapy on dynamic cardiac function in critically ill patients with stress-induced hyperglycemia. World J Diabetes 2025; 16(7): 107767
URL: https://www.wjgnet.com/1948-9358/full/v16/i7/107767.htm
DOI: https://dx.doi.org/10.4239/wjd.v16.i7.107767