Association of dietary index for gut microbiota and all-cause and cardiovascular mortality in patients with diabetes or prediabetes

Table 2 Association of diabetes and prediabetes all-cause mortality and cardiovascular risk with dietary index for gut microbiota

	Model 11		Model 22		Model 33
	HR (95%CI)	P value	HR (95%CI)	P value	HR (95%CI)	P value
All-cause mortality
DI-GM	0.99 (0.95-1.02)	0.42	0.93 (0.89-0.96)	< 0.0001	0.96 (0.93-1.00)	0.05
DI-GM quartiles
Q1	Reference	Reference	Reference	Reference	Reference	Reference
Q2	0.96 (0.80-1.14)	0.63	0.89 (0.75-1.06)	0.20	0.94 (0.80-1.10)	0.45
Q3	1.01 (0.86-1.19)	0.90	0.86 (0.73-1.01)	0.06	0.93 (0.80-1.09)	0.38
Q4	0.91 (0.76-1.08)	0.27	0.68 (0.57-0.82)	< 0.0001	0.83 (0.69-0.99)	0.03
P for trend	0.608		< 0.001		0.283
Cardiovascular mortality
DI-GM	0.96 (0.90-1.02)	0.15	0.90 (0.84-0.95)	< 0.001	0.93 (0.87-0.99)	0.02
DI-GM quartiles
Q1	Reference	Reference	Reference	Reference	Reference	Reference
Q2	0.90 (0.66-1.23)	0.52	0.85 (0.62-1.17)	0.32	0.85 (0.62-1.16)	0.31
Q3	0.93 (0.72-1.20)	0.60	0.78 (0.61-1.01)	0.06	0.81 (0.63-1.06)	0.12
Q4	0.85 (0.61-1.18)	0.33	0.62 (0.45-0.86)	0.005	0.75 (0.54-1.00)	0.05
P for trend	0.604		0.013		0.916

¹Model 1: No adjustments made.

²Model 2: Adjusted for age, sex, race.

³Model 3: Adjusted for age, sex, race, poverty income ratio, smoke, alcohol, BMI, cancer, hypertension, CVD, marital and education.

HR: Hazard ratio; DI-GM: Dietary index for gut microbiota.