Efficacy of Xiaokeqing granules and lifestyle intervention in treating prediabetes mellitus considering metabolomic biomarkers: A randomised controlled trial

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Jul 15, 2025 (publication date) through Aug 9, 2025

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Jul 15, 2025; 16(7): 105219
Published online Jul 15, 2025. doi: 10.4239/wjd.v16.i7.105219

Table 8 Metabolite features of least absolute shrinkage and selection operator regression analysis

Feature	Coefficient
Dimethylformamide	-0.36107
5-Hydroxy-L-Tryptophan	10.6295
Lanthionine ketimine	0.750093
5-Nitro-2-phenylpropylaminobenzoic acid	0.214502
Tyr Leu	0.242158
N-Nervonoyl methionine	12.02622
Calcitroic acid	4.998331
Valylasparagine	1.677792
4-Epitetracycline	0.702722
Naringenin 7-sulfate	0.512388
Stearoyllactic acid	-1.58267
N-Oleoyl glutamine	2.505959
1-Nitro-7-glutathionyl-8-hydroxy-7,8-dihydronaphthalene	0.374231
2-(5-carboxypentanoylamino) benzoic acid	0.332139
Flurenol	0.023748

Citation: Zhao JD, Guo MZ, Zhang Y, Zhu SH, Wang YT, Zhang YP, Liu X, Cheng S, Wang F, Xu Q, Ruan NB, Fang ZH. Efficacy of Xiaokeqing granules and lifestyle intervention in treating prediabetes mellitus considering metabolomic biomarkers: A randomised controlled trial. World J Diabetes 2025; 16(7): 105219
URL: https://www.wjgnet.com/1948-9358/full/v16/i7/105219.htm
DOI: https://dx.doi.org/10.4239/wjd.v16.i7.105219