Correlation between serum advanced glycation end-products and their receptor-mediated oxidative stress and perinatal outcomes in gestational diabetes mellitus

doi:10.4239/wjd.v16.i6.104177

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Jun 15, 2025; 16(6): 104177
Published online Jun 15, 2025. doi: 10.4239/wjd.v16.i6.104177

Table 4 Logistic regression of risk factors for adverse perinatal outcomes

Measurement	β	SE	Wald	P value	Odd ratios	Unadjusted 95%CI	Adjusted 95%CI
Constant	-11.302	9.945	1.292	0.256	0.000		-
AGEs	0.054	0.012	21.838	0.000¹	1.056	8.562-169.764	1.032-1.080
sRAGE	-0.053	0.014	14.451	0.000¹	0.949	0.012-0.150	0.923-0.975
SOD	-0.025	0.102	0.058	0.810	0.976	0.268-1.267	0.799-1.191
MDA	0.113	0.552	0.042	0.838	1.119	1.461-7.553	0.380-3.299

¹Statistically significant difference.

AGE: Advanced glycation end-product; sRAGE: Soluble advanced glycation end-product receptor; SOD: Superoxide dismutase; MDA: Malondialdehyde.

Citation: Zhang Y, Li T, Wang ZH, Liu Y. Correlation between serum advanced glycation end-products and their receptor-mediated oxidative stress and perinatal outcomes in gestational diabetes mellitus. World J Diabetes 2025; 16(6): 104177
URL: https://www.wjgnet.com/1948-9358/full/v16/i6/104177.htm
DOI: https://dx.doi.org/10.4239/wjd.v16.i6.104177