Correlation between serum advanced glycation end-products and their receptor-mediated oxidative stress and perinatal outcomes in gestational diabetes mellitus

Table 2 Comparison of serum indexes

Time Frame	Grouping	AGEs (ng/L)	sRAGE (ng/L)	SOD (U/L)	MDA (μmol/L)
At 24-28 weeks of pregnancy	Control group (n = 85)	385.26 ± 51.25	374.25 ± 54.26	92.25 ± 5.21	3.31 ± 0.64
	GDM group (n = 126)	461.25 ± 69.25	281.25 ± 39.58	83.65 ± 3.25	4.86 ± 0.81
	t value	8.955	16.37	18.50	14.14
	P value	< 0.00011	< 0.00011	< 0.00011	< 0.00011
Before delivery	Control group (n = 85)	401.25 ± 42.65	368.56 ± 51.24	90.36 ± 5.08	3.28 ± 0.61
	GDM group (n = 126)	475.26 ± 62.58	274.15 ± 33.59	80.34 ± 3.41	5.24 ± 0.84
	t value	8.546	18.40	16.99	18.69
	P value	< 0.00011	< 0.00011	< 0.00011	< 0.00011

¹Statistically significant difference.

AGE: Advanced glycation end-product; sRAGE: Soluble advanced glycation end-product receptor; SOD: Superoxide dismutase; MDA: Malondialdehyde; GDM: Gestational diabetes mellitus.