Associations of nontraditional lipoprotein ratios with future cardiovascular events in patients with type 2 diabetes mellitus

Figure 3 Subgroup and interaction analyses of the associations of nontraditional lipoprotein ratios with major adverse cardiovascular events. The study population was stratified by sex (female vs male), race (non-White vs White), age (< 65 years vs ≥ 65 years), body mass index (< 28 kg/m²vs ≥ 28 kg/m²), duration of type 2 diabetes mellitus (< 10 years vs ≥ 10 years), previous cardiovascular events (no vs yes), previous heart failure (no vs yes), and HbA1c (< 8% vs ≥ 8%). Adjustments for sex, age, race, educational level, depression, cigarette-smoking status, duration of type 2 diabetes mellitus, previous cardiovascular events, previous heart failure, previous hypertension, body mass index, systolic blood pressure, diastolic blood pressure, hemoglobin A1c, fasting blood glucose, estimated glomerular filtration rate, insulin use, biguanide use, beta-blocker use, and statin use. A: Total cholesterol/high-density lipoprotein cholesterol (HDL-C); B: Low-density lipoprotein cholesterol/HDL-C; C: Non-HDL-C/HDL-C; D: Remnant cholesterol/HDL-C. TC: Total cholesterol; HDL-C: High-density lipoprotein cholesterol; LDL-C: Low-density lipoprotein cholesterol; RC: Remnant cholesterol; BMI: Body mass index; T2DM: Type 2 diabetes mellitus; HbA1c: Hemoglobin A1c; HR: Hazard ratio; CI: Confidence interval.