Single-nucleotide polymorphisms in genes involved in folate metabolism or selected other metabolites and risk for gestational diabetes mellitus

Table 5 Gene-environment interaction model for gestational diabetes mellitus susceptibility

The best model	Tr.BA1	Te.BA2	P value	CVC3
Pre-pregnancy BMI	0.6244	0.6242	0.001	10/10
Pre-pregnancy BMI rs10830963	0.6418	0.6235	0.001	9/10
Pre-pregnancy BMI rs10830963 per capita annual household income	0.6671	0.6331	0.001	6/10
Pre-pregnancy BMI rs10830963 per capita annual household income rs4721	0.7071	0.5777	0.001	5/10
Pre-pregnancy BMI delivery age per capita annual household income rs1801133 rs1387153	0.7756	0.5554	0.055	6/10

¹Training Bal.Acc, training balanced accuracy, the accuracy in the training set, with a range of 0-1, where the larger the value, the higher the accuracy.

²Testing Bal.Acc, testing balanced accuracy, the accuracy in the testing set, with a range of 0-1, where the larger the value, the higher the accuracy.

³Cross-verifying consistency.

CVC: Cross-validation consistency; BMI: Body mass index.