Exercise training benefits pancreatic islet by modulating the insulin-like growth factor 1/phosphatidylinositol 3-kinase/protein kinase B pathway

Figure 1 Features of the diabetic rat model and the impact of physical activity. A: Measurement of rat body weight post-experiment; B: Recording of daily average food intake for rats during the experiment; C: Pancreatic morphology of rats from the four groups (× 400 magnification); D: Measurement of the islet longest diameter through observation of pancreatic sections; E: Measurement of islet area through observation of pancreatic sections; F: Measurement of islet number through observation of pancreatic sections. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001 vs the control sedentary group; ^dP < 0.05, ^eP < 0.01 vs the diabetic sedentary group. D-Ex: The diabetic exercise group; D-Sed: The diabetic sedentary group; C-Ex: The control exercise group; C-Sed: The control sedentary group.