Neurophysiological mechanisms of electroacupuncture in regulating pancreatic function and adipose tissue expansion

Figure 3 TRPV1-mediated acupuncture modulates the discharge patterns of the pancreatic intrinsic nervous system. A and B: The impact of manual acupuncture (MA) at Tianshu (ST25) acupoint on pancreatic intrinsic nervous system (PINS) activity and the corresponding discharge frequency in wild-type (WT) mice; C and D: The influence of MA at ST25 on PINS activity and discharge frequency in TRPV1 knockout (TRPV1^-/-) mice; E and F: The effect of MA at ST25 on peripancreatic adipose tissue (PAT) activity and associated discharge frequency in WT mice; G and H: The alteration in PAT activity and discharge frequency following MA at Tianshu (ST25) acupoint in TRPV1^-/- mice (n = 7). ^aP < 0.01 compared to the dur-MA group; ^bP < 0.01 compared to the pre-MA group and MA, manual acupuncture. TRPV1: Transient receptor potential vanilloid subfamily member 1; MA: Manual acupuncture.