Effect of glucagon-like peptide-1 receptor agonists on gastric mucosal visibility during upper endoscopy in Asian patients with diabetes

doi:10.4239/wjd.v16.i12.112694

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Dec 15, 2025; 16(12): 112694
Published online Dec 15, 2025. doi: 10.4239/wjd.v16.i12.112694

Table 2 Procedural outcomes of glucagon-like peptide-1 receptor agonist users and dipeptidyl peptidase 4 inhibitor users before and after matching, n (%)

Characteristic	Before matching (n = 733)				After matching (n = 493)
Characteristic	Total (n = 733)	GLP-1RA (n = 208)	DPP4i (n = 525)	P value	Total (n = 493)	GLP-1RA (n = 198)	DPP4i (n = 295)	P value
Inadequate gastric mucosal visibility	27 (3.7)	19 (9.1)	8 (1.5)	< 0.0001	21 (4.3)	17 (8.6)	4 (1.4)	0.0007
Aborted EGD	21 (2.9)	16 (7.7)	5 (1.0)	< 0.0001	17 (3.4)	15 (7.6)	2 (0.7)	0.0011
Repeat EGD	21 (2.9)	16 (7.7)	5 (1.0)	< 0.0001	17 (3.4)	15 (7.6)	2 (0.7)	0.0011
Pulmonary aspiration	0 (0.0)	0 (0.0)	0 (0.0)	NA	0 (0.0)	0 (0.0)	0 (0.0)	NA

GLP-1RA: Glucagon-like peptide-1 receptor agonist; DPP4i: Dipeptidyl peptidase 4 inhibitor; EGD: Esophagogastroduodenoscopy; NA: Not applicable.

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Citation: Oh YE, Kim TS, Chi SA, Park HJ, Min YW, Lee H, Lee JH, Rhee PL, Kim JJ, Min BH. Effect of glucagon-like peptide-1 receptor agonists on gastric mucosal visibility during upper endoscopy in Asian patients with diabetes. World J Diabetes 2025; 16(12): 112694
URL: https://www.wjgnet.com/1948-9358/full/v16/i12/112694.htm
DOI: https://dx.doi.org/10.4239/wjd.v16.i12.112694

Oh YE, Kim TS, Chi SA, Park HJ, Min YW, Lee H, Lee JH, Rhee PL, Kim JJ, Min BH. Effect of glucagon-like peptide-1 receptor agonists on gastric mucosal visibility during upper endoscopy in Asian patients with diabetes. World J Diabetes 2025; 16(12): 112694 [PMID: 41480609 DOI: 10.4239/wjd.v16.i12.112694]

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