Association of ICAM-1 Gene Polymorphisms with Diabetic Retinopathy in T2DM Patients from Northern India: Case-control and meta-analysis

Table 6 Meta-analysis results of intercellular adhesion molecule-1 Lys469Glu polymorphism under different genetic models in overall and Asian populations

Model		Allelic model (G vs A)			Recessive model (GG vs AG + AA)			Dominant model (AG + GG vs AA)
Ethnicity		Overall	Asian	Caucasian	Overall	Asian	Caucasian	Overall	Asian	Caucasian
Number of studies		9	8	1	9	8	1	9	8	1
Test of association	Model	Random	Random	Fixed	Random	Random	Fixed	Random	Random	Fixed
	OR (95%CI)	0.99 (0.79-1.26)	0.94 (0.74-1.21)	1.44 (1.06-1.95)	1.08 (0.80-1.47)	0.99 (0.74-1.34)	2 (1.15-3.48)	0.951 (0.69-1.31)	0.90 (0.64-1.28)	1.40 (0.86-2.27)
	P value	0.987	0.679	0.021	0.623	0.961	0.014	0.951	0.566	0.173
Test of heterogeneity	I2	0.79	0.79	NA	0.57	0.48	NA	0.76	0.77	NA
	P value	< 0.001	< 0.001	NA	0.02	0.06	NA	< 0.001	< 0.001	NA
Egger’s test P value		0.866	0.796	NA	0.852	0.759	NA	0.857	0.782	NA

OR: Odds ratio; CI: Confidence interval.