Real-world evidence for herbal medicine benefit in 9728 type 2 diabetes patients-peridonotitis risk and ambulatory care utilization

Table 2 Risk of periodontitis for type 2 diabetes subjects with and without adding medicinal herbs

Participants	Event	PY	Incidence	Crude HR (95%CI)	Adjusted HR1 (95%CI)
Nonusers of medicinal herbs	4991	63852.56	78.16	1	1
Users of medicinal herbs	4306	66855.04	64.41	0.80 (0.75-0.84)	0.79 (0.76-0.83)
Group 1 (use for 31-365 days)	3823	56306.79	67.89	0.86 (0.81-0.90)	0.84 (0.80-0.87)
Group 2 (use for 366-730 days)	340	6800.35	50.01	0.64 (0.56-0.70)	0.60 (0.54-0.67)
Group 3 (use more than 730 days)	143	3747.90	38.15	0.49 (0.41-0.57)	0.48 (0.41-0.57)

¹Model adjusted for age, gender, monthly income, residential area and Charlson-Deyo comorbidity index.

PY: Person-years; HR: Hazard ratio; 95%CI: 95% confidence interval.