Correlation of gut microbiota metabolite trimethylamine N-oxide with inflammatory levels and osteoporosis in patients with diabetic nephropathy

Figure 3 Correlation analysis between trimethylamine N-oxide and gastrointestinal flora abundance in patients with diabetic nephropathy. Matrix scatter plot. r represents the correlation coefficient; polynomial fitting was used to explore potential nonlinear trends; Pearson correlation coefficient r is used to quantify the strength of relationships between variables. Histograms on the diagonal indicate the distribution patterns of the data. In the scatter plots, an upward-sloping trend line indicates a positive correlation, while a downward-sloping line indicates a negative correlation. The area within the ellipse represents the cluster of data points, whereas points outside the ellipse are considered outliers. ^aP < 0.05. TMAO: Trimethylamine N-oxide.