Serum alpha-1-microglobulin as a predictor of multiple complications in type 2 diabetes mellitus patients

Figure 2 Association of the serum alpha-1-microglobulin level with the risk of different diabetic complications according to restricted cubic splines. A: Diabetic nephropathy; B: Diabetic retinopathy; C: Diabetic peripheral neuropathy; D: Left ventricular hypertrophy. The models were adjusted for age, sex, body mass index, smoking, alcohol consumption, systolic blood pressure, diastolic blood pressure, hypertension, hyperlipidaemia, coronary heart disease, antihypertensive drugs, lipid-lowering drugs, antidiabetic drugs, fasting blood glucose, glycated haemoglobin, total cholesterol, triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, uric acid, estimated glomerular filtration rate, alanine aminotransferase, aspartate aminotransferase, white blood cell, C-reactive protein, and left ventricular ejection fraction. reference values for estimation were set at median values of alpha-1-microglobulin. α1-MG: Alpha-1-microglobulin.