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©The Author(s) 2025.
World J Diabetes. Oct 15, 2025; 16(10): 111309
Published online Oct 15, 2025. doi: 10.4239/wjd.v16.i10.111309
Table 1 Risk factors for gestational diabetes mellitus
Risk factors
Overweight or obese adults (BMI ≥ 25 kg/m2, ≥ 23 kg/m2 for Asians) with at least one of the following risk factors:
    History of diabetes in a first-degree relative
    High-risk race or ethnicity (e.g., African American, Latin American)
    History of cardiovascular disease
    HDL cholesterol level < 35 mg/dL (< 0.9 mmol/L) and/or triglyceride level > 250 mg/dL (> 2.8 mmol/L)
    Polycystic ovary syndrome
    Physical inactivity
    Other clinical conditions associated with insulin resistance (obesity, acanthosis nigricans)
Prediabetes (HbA1c ≥ 5.7%) and impaired fasting and glucose tolerance
Individuals previously diagnosed with GDM
Individuals afflicted with HIV, those utilizing medications that elevate the risk of diabetes, and those with a history of pancreatitis. Additionally, ACOG:
    History of birth over 4000 g
    Hypertension (140/90 mmHg or those taking antihypertensive medication)


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