Blood glucose variability impacts heart rate dynamics in older type 2 diabetic and coronary heart disease patients

doi:10.4239/wjd.v16.i10.110722

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Oct 15, 2025; 16(10): 110722
Published online Oct 15, 2025. doi: 10.4239/wjd.v16.i10.110722

Table 4 Comparison of heart rate variability time-domain indicators between the two groups

Group	Number of cases	SDNN (ms)	SDANN (ms)	SDNNindex (ms)	rMSSD (ms)	pNN50 (%)
Normoglycemia group	68	113.62 ± 24.83	101.47 ± 19.86	30.45 ± 10.64	24.15 ± 6.07	7.99 ± 4.06
Abnormal blood sugar fluctuation group	75	96.45 ± 15.87	85.74 ± 13.62	22.12 ± 6.40	17.42 ± 3.88	5.01 ± 2.25
t value		22.016	26.432	9.013	8.764	5.216
P value		0.000	0.000	0.000	0.000	0.035

SDNN: Standard deviation of normal-to-normal interval; SDANN: Standard deviation of the average normal-to-normal interval; SDNNindex: Standard deviation of normal-to-normal intervals over every 5-minute period; rMSSD: Root mean square of successive differences; pNN50: Percentage of normal-to-normal intervals differing by > 50 ms.

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Citation: Li AQ, Zhang F. Blood glucose variability impacts heart rate dynamics in older type 2 diabetic and coronary heart disease patients. World J Diabetes 2025; 16(10): 110722
URL: https://www.wjgnet.com/1948-9358/full/v16/i10/110722.htm
DOI: https://dx.doi.org/10.4239/wjd.v16.i10.110722

Li AQ, Zhang F. Blood glucose variability impacts heart rate dynamics in older type 2 diabetic and coronary heart disease patients. World J Diabetes 2025; 16(10): 110722 [PMID: 41113498 DOI: 10.4239/wjd.v16.i10.110722]

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