In vitro and clinical evaluation of platelet-rich plasma combined with angioplasty in diabetic foot treatment

Figure 4 Tube formation assay of human umbilical vein endothelial cells. A and B: Observation of tube formation in the (A) control group and (B) platelet-rich plasma (PRP)-treated group of human umbilical vein endothelial cells; C: Analysis of mesh number in the control and PRP-treated groups; D: Analysis of node number in the control and PRP-treated groups. Significant differences in experimental data were analyzed using t tests, and all assays were performed in triplicate. ^bP < 0.01 vs the control (CTRL); ^cP < 0.001 vs the CTRL group. The magnification of the inverted microscope was 100 ×. CTRL: The control group; PRP: Platelet-rich plasma.