In vitro and clinical evaluation of platelet-rich plasma combined with angioplasty in diabetic foot treatment

Figure 3 Cell migration assay. A: Migration status of human umbilical vein endothelial cells (HUVECs) in the control and platelet-rich plasma (PRP)-treated groups under high-glucose conditions; B: Statistical analysis of migration data of HUVECs in the control and PRP-treated groups under high-glucose conditions; C: Migration status of human dermal fibroblasts (HSFs) in the control and PRP-treated groups under high-glucose conditions; D: Statistical analysis of migration data of HSFs in the control and PRP-treated groups under high-glucose conditions; E: Migration status of human immortalized keratinocytes (HaCaTs) in the control and PRP-treated groups under high-glucose conditions; F: Statistical analysis of migration data of HaCaTs in the control and PRP-treated groups under high-glucose conditions. Significant differences in experimental data were analyzed using two-way analysis of variance, and all assays were performed in triplicate. ^cP < 0.001 vs the control group. The magnification of the inverted microscope was 100 ×. CTRL: The control group; PRP: Platelet-rich plasma.