In vitro and clinical evaluation of platelet-rich plasma combined with angioplasty in diabetic foot treatment

Table 1 Patient characteristics in each group, n (%)

Characteristics	Endovascular angioplasty (n = 105)	PRP + endovascular angioplasty (n = 103)	P value
Males	63 (60)	61 (59.2)	0.73
Age, mean ± SD (years)	75.37 ± 8.37	74.54 ± 8.27	0.19
Smoking	34 (32.3)	32 (31.1)	0.90
Renal failure, n	0	0
Hypertension	76 (72.3)	74 (71.8)	0.96
Hypercholesterolaemia	49 (46.7)	51 (50)	0.91
Rutherford classification			0.98
5	93 (88.5)	91 (88.3)
6	12 (11.5)	12 (12.7)
Wagner classification			0.93
1	1 (1)	2 (1.9)
2	45 (43.9)	46 (44.7)
3	40 (37.7)	32 (31.1)
4	17 (16.2)	19 (18.4)
5	2 (1.9)	4 (3.9)
Skin temperature			0.19
0	1 (1)	2 (1.9)
1	26 (24.8)	25 (24.3)
2	56 (53.3)	60 (58.3)
3	22 (20.9)	18 (17.5)
Ankle-Brachial index, mean ± SD	0.67 ± 0.14	0.65 ± 0.11	0.68
Vascular occlusion evaluation			0.82
1	29 (27.6)	32 (31.1)
2	65 (61.9)	58 (56.3)
3	11 (10.5)	13 (12.6)
Ulcer healing area, mean ± SD (cm2)	12.85 ± 1.97	12.56 ± 2.02	0.23

Normality assumptions were tested by the Shapiro-Wilk test. PRP: Platelet-rich plasma.