Clopidogrel delays and can reverse diabetic nephropathy pathogenesis in type 2 diabetic db/db mice

Figure 3 Clopidogrel reduces the production of fibronectin and collagen I in the kidneys of db/db mice. A: Representative immunohistochemical staining. Magnification: × 400; B: Quantitative analysis of fibronectin protein and collagen I protein. Data are shown as mean ± SD values of n = 6 mice per group. ^aP < 0.05 vs wild type mice; ^bP < 0.05 vs db/db mice. FN: Fibronectin; WT: Wild type; db/db: db/db mice; Clo: Clopidogrel.