Role of cannabinoids and the endocannabinoid system in modulation of diabetic cardiomyopathy

Figure 2 Stages of diabetic cardiomyopathy progression. Diabetic cardiomyopathy progresses from early development of hypertrophy and diastolic dysfunction that then progress to decreased systolic activity, apoptosis and cardiac fibrosis leading to severe impairment in both systolic and diastolic functions. AGE: Advanced glycation end products.