Roles of transient receptor potential channel 6 in glucose-induced cardiomyocyte injury

Figure 6 Effects of SAR7334 and KN-93 on high-glucose-induced apoptosis of H9C2 cells. A: Apoptosis rate of H9C2 cells in each group was detected by flow cytometry. n = 5, unpaired t-test, ^aP < 0.0001; B: Effects of SAR7334 and KN-93 on the expression of apoptosis related proteins Bax, cleaved Caspase 3 (CC3), and BCl2 in H9C2 cells induced by high glucose. n = 5, unpaired t-test, ^bP < 0.001. n.s.: No statistical difference; C and D: Expression of apoptosis protein CC3 detected by immunofluorescence. n = 5, unpaired t-test, ^aP < 0.0001, ^bP < 0.001, ^cP < 0.01. Scale bars = 10 μm. HG: High-glucose; LG: Low-glucose.