Age at diagnosis of type 2 diabetes and cardiovascular risk factor profile: A pooled analysis

Table 4 Results from linear regression models investigating the effect of age at diagnosis on each cardiovascular risk factor

	Model 1		Model 2		Model 3
	Estimate	n	Estimate	n	Estimate	n
Weight (kg)	-0.32 [(-0.51) to (-0.14)]a	1409	-0.45 [(-0.60) to (-0.31)]a	1408	-0.67 [(-0.82) to (-0.52)]a	1394
BMI (kg/m2)	-0.11 [(-0.19) to (-0.02)]b	1409	-0.15 [(-0.23) to (-0.07)]a	1408	-0.18 [(-0.25) to (-0.10)]a	1394
Waist circumference (cm)	-0.21 [(-0.32) to (-0.09)]a	1403	-0.23 [(-0.41) to (-0.05)]b	1402	-0.32 [(-0.49) to (-0.14)]a	1388
Body fat (%)	-0.10 (-0.80 to 0.60)	1076	-0.16 (-0.85 to 0.53)	1075	-0.11 (-0.43 to 0.20)	1073
HbA1c (%)	-0.04 [(-0.04) to (-0.03)]a	1370	-0.03 [(-0.04) to (-0.03)]a	1369	-0.03 [(-0.04) to (-0.03)]a	1356
Total cholesterol (mmol/L)	-0.01 (-0.01 to 0.00)	1352	-0.02 [(-0.02) to (-0.01)]a	1351	-0.01 [(-0.02) to (-0.01)]a	1337
LDL cholesterol (mmol/L)	-0.01 (-0.01 to 0.00)b	1308	-0.01 [(-0.02) to (-0.01)]a	1307	-0.01 [(-0.02) to (-0.01)]a	1294
HDL cholesterol (mmol/L)	0.00 (0.00 to 0.01)	1338	0.00 (0.00 to 0.01)	1337	0.01 (0.00 to 0.01)	1323
Triglycerides (mmol/L)	-0.01 (-0.03 to 0.00)	1351	-0.02 [(-0.03) to (-0.01)]b	1350	-0.02 [(-0.03) to (-0.01)]a	1336
Systolic BP (mmHg)	0.24 (0.14 to 0.35)a	1408	0.31 (0.11 to 0.51)b	1407	0.24 (0.02 to 0.45)b	1393
Diastolic BP (mmHg)	-0.10 (-0.21 to 0.02)	1408	-0.20 [(-0.29) to (-0.12)]a	1407	-0.22 [(-0.30) to (-0.14)]a	1393

^aP < 0.01.

^bP < 0.05.

Data presented as coefficient. Model 1: Unadjusted univariable model, Model 2: Adjusted for duration of T2D, Model 3: Adjusted for duration of T2D, sex, ethnicity and smoking status. LDL: Low-density lipoprotein; HDL: High-density lipoprotein; BMI: Body mass index; T2DM: Type 2 diabetes mellitus; HbA1c: Glycaemic control; BP: Blood pressure.