Effectiveness and safety of human umbilical cord-mesenchymal stem cells for treating type 2 diabetes mellitus

Figure 2 Assessment of the effectiveness of human umbilical cord blood-mesenchymal stem cell treatment. A: Fasting plasma glucose tested on day 0 ± 3, day 14 ± 3, day 21 ± 3, day 28 ± 3, and day 84 ± 3; B-D: 2-h postprandial blood glucose, fasting C-peptide, and 2-h postprandial C-peptide tested on day 0 ± 3, day 28 ± 3, and day 84 ± 3; E: Glycosylated hemoglobin A1c levels tested on day 0 ± 3, day 28 ± 3, and day 84 ± 3; F and G: Homeostasis model assessment of insulin resistance and homeostasis model assessment of β-cell function calculated on day 0 ± 3, day 28 ± 3, and day 84 ± 3. ^aP < 0.05, ^bP < 0.01. FPG: Fasting plasma glucose; P2BG: 2-h postprandial blood glucose; FCP: Fasting C-peptide; P2CP: 2-h postprandial C-peptide; HbA1c: Glycosylated hemoglobin A1c; HOMA-IR: Homeostasis model assessment of insulin resistance; HOMA-β: Homeostasis model assessment of β-cell function.