Polycystic ovary syndrome and type 2 diabetes mellitus: A state-of-the-art review

Table 2 Guidelines regarding oral glucose tolerance test upon diagnosis of Polycystic ovary syndrome

Ref.	OGTT recommended upon diagnosis in all women with PCOS	Follow-up with OGTT
Joint AACE/ACE and AE-PCOS society[56]	Yes	(1) Yearly in women with IGT; and (2) Every 1–2 years based on BMI (not specified) and family history of T2D
Australian NHMRC[57]	Recommended if one or more criteria exist: (1) BMI > 25 kg/m2 or in Asians > 23 kg/m2; (2) History of IFG, IGT, GDM; (3) Family history of T2D; (4) Arterial hypertension; and (5) High-risk ethnicity	Every 1-3 years, based on presence of other diabetesrisk factors
Endocrine Society[55]	Yes	Every 3–5 years (Sooner if additional risk factors for T2D develop)
Royal College of Obstetricians andGynecology[59]	Recommended if one or more criteria exist: (1) BMI ≥ 25 kg/m2; (2) Age ≥ 40 years; (3) Previous GDM; and (4) Family history of T2D	Yearly in women with IGT or IFG
AE-PCOS Society[58]	Recommended if one or more criteria exist: (1) BMI ≥ 30 kg/m2; (2) Age ≥ 40 years; (3) Previous GDM; and (4) Family history of T2D	Every 2 years in women with risk factors (Sooner if additional risk factors for T2D develop)
ESHRE and ASRM[60]	Recommended if BMI ≥ 27 kg/m2	Not specified

OGTT: Oral glucose tolerance test; PCOS: Polycystic ovary syndrome; T2D: type 2 diabetes mellitus; BMI: Body mass index; IFG: Impaired fasting glucose; IGT: Impaired glucose tolerance.