Clinical significance of serum miR-129-5p in patients with diabetes mellitus presenting macrovascular complications

Table 3 Relationship between the expression of serum miR-129-5p and clinical factors in diabetic macrovascular complications

Parameter	No. of cases (n = 62)	miR-129 level		χ2	P value
		High (n = 24)	Low (n = 38)
Gender
Male	33	15	18	1.353	0.245
Female	29	9	20
Age (yr)
≥ 60	31	15	16	2.447	0.118
< 60	31	9	22
BMI (kg/m2)
≥ 24	42	13	29	3.302	0.069
0 < 24	20	11	9
Smoking history
Yes	16	10	6	5.144	0.023
No	46	14	32
DM family history
Yes	25	13	12	3.119	0.077
No	37	11	26
Duration of disease (yr)
≥ 10	29	16	13	6.224	0.013
< 10	33	8	25
HBP
Yes	28	12	16	0.37	0.543
No	34	12	22
HbA1c (%)
≥ 10 .28	33	18	15	7.457	0.006
< 10.28	29	6	23
FBG (mmol/L)
≥ 10 .34	21	10	11	1.062	0.303
< 10.34	41	14	27
PBS 1 h (mmol/L)
≥ 13.11	36	15	21	0.316	0.574
< 13.11	26	9	17
PBS 2 h (mmol/L)
≥ 13.65	33	14	19	0.41	0.522
< 13.65	29	10	19
TG (mmol/L)
≥ 1.867	20	5	15	2.339	0.126
< 1.867	42	19	23
TCHO (mmol/L)
≥ 5.047	24	9	15	0.024	0.876
< 5.047	38	15	23
HDL-c (mmol/L)
≥ 1.303	30	10	20	0.708	0.4
< 1.303	32	14	18
LDL-c (mmol/L)
≥ 3.735	27	11	16	0.083	0.773
< 3.735	35	13	22

BMI: Body mass index; DM: Diabetes mellitus; OGTT: Oral glucose tolerance test; HbA1c: Hemoglobin A1c; TG: Triglyceride; TCHO: Total cholesterol; HDL-c: High-density lipoprotein-cholesterol; LDL-c: Low-density lipoprotein-cholesterol.