Effect of oligofructose on resistance to postoperative high-fat diet-induced damage of metabolism in diabetic rats after sleeve gastrectomy

Figure 1 Areas under the curves for oral glucose tolerance test, homeostasis model assessment of insulin resistance, and serum insulin levels. A: Areas under the curves for oral glucose tolerance test; B: Homeostasis model assessment of insulin resistance; C-F: Serum insulin levels measured during the oral glucose tolerance test at baseline and 2, 12, and 24 wk after surgery [^aP < 0.001, SHAM vs sleeve gastrectomy (SG); ^bP < 0.001, SHAM vs SG-oligofructose (SG-OF); ^cP < 0.001, SG vs SG-OF]. The concentration of insulin during the oral glucose tolerance test was analyzed using mixed model ANOVA followed by Bonferroni post hoc comparison. The P value is shown in the rectangular frame. A statistically significant difference was considered at P < 0.05. AUC_OGTT: Areas under the curves for oral glucose tolerance test; SG-OF: Sleeve gastrectomy-oligofructose; HOMA-IR: Homeostasis model assessment of insulin resistance.