Altered spontaneous brain activity in patients with diabetic optic neuropathy: A resting-state functional magnetic resonance imaging study using regional homogeneity

doi:10.4239/wjd.v12.i3.278

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Mar 15, 2021; 12(3): 278-291
Published online Mar 15, 2021. doi: 10.4239/wjd.v12.i3.278

Table 2 Brain regions with significant differences in regional homogeneity between the healthy control and diabetic optic neuropathy groups

ReHo	DON group and HCs				MNI coordinates
ReHo	Brain areas	BA	Peak t-values	Voxels	X	Y	Z
DON < HCs
1	RMFG	45	4.4606	185	39	36	9
2	LAC	32	4.6582	195	-9	30	24
3	SFG/LFSO	48	4.0066	214	-30	36	15

Statistical threshold set at voxels with P < 0.05 for multiple comparisons using Gaussian random-field theory (z > 2.3, P < 0.05, cluster size, > 40, AlphaSim-corrected). ReHo: Regional homogeneity; DON: Diabetic optic neuropathy; HCs: Healthy controls; BA: Brodmann area; MNI: Montreal Neurological Institute; RMFG: Right middle frontal gyrus; LAC: Left anterior cingulate; SFG: Superior frontal gyrus; LFSO: Left frontal superior orbital gyrus.

Citation: Guo GY, Zhang LJ, Li B, Liang RB, Ge QM, Shu HY, Li QY, Pan YC, Pei CG, Shao Y. Altered spontaneous brain activity in patients with diabetic optic neuropathy: A resting-state functional magnetic resonance imaging study using regional homogeneity. World J Diabetes 2021; 12(3): 278-291
URL: https://www.wjgnet.com/1948-9358/full/v12/i3/278.htm
DOI: https://dx.doi.org/10.4239/wjd.v12.i3.278